Evaluate the severity of chronic Helicobacter pylori infection with some blood parameters

Objective: The objective of this study was to assess the Vitamin D levels, vitamin B, iron and ferritin among Helicobacter pylori patients and investigate potential correlations with bacterial infection severity. Methods: The current study included 187 patients (male and female aged from 4 to 60 years) suffering from gastrointestinal symptoms introduced to the doctor and blood sample collected from December 2023 to April 2024 in a private lab (hemoglobin laboratory in Baghdad, Iraq). A five-ml venous blood sample was collected for detection the infection with H.pylori IgG using VIDUS, while Serum vitamin D, vitamin B12, Iron and ferritin were estimated by Cobas e411. Results: The results shown a high significance correlation at p value 0.01 between infected with H.pylori in Vitamin D, B, Iron and ferritin deficiency as well as the deficiency increased with elevation of titration of bacterial antibodies. Conclusion: Vitamin D, vitamin B, iron, and ferritin levels are all lower in H. pylori patients, and this lower level is correlated with the severity of the injury, so reducing the severity of infection may be accomplished by taking supplements or receiving medical attention.