Impact of obesity on thyroid profile and thyroid autoantibodies parameters in obese subjects with and without metabolic syndrome

Obesity is a chronic disease that is associated with a wide range of complications affecting many different aspects of physiology. The complications of obesity can reduce the quality of life and shorten the lifespan. This study aims to investigate the impact of obesity on thyroid profile and thyroid autoantibody parameters in obese subjects with and without metabolic syndrome (MetS). The study includes 145 Iraqi participants (60 males and 85 females), they were divided into 65 obese individuals with MetS, 50 obese individuals without MetS, and 25 healthy controls; the average age of the participants ranged from 20-60 years. Blood samples (5ml) were collected from all the study subjects’ groups by intravenous suction. Thyroid hormones (T3, T4, and TSH) and thyroid autoantibodies (TPO-Ab, TG-Ab, and TSHR-Ab) were measured using ELISA kits. The results revealed a significant (P