Time-Dependent Changes Provide Better Prognostic Insights than Static Measurements of BMI in Gastric Cancer Patients
Abstract
In gastric cancer (GC) patients, malnutrition is associated with a worse prognosis. Decreases in body mass index (BMI) can reflect malnutrition. Here, we determined whether preoperative time-dependent changes (Δ/day) in BMI provide better prognostic insights than single point-in-time measurements of BMI. A single-center retrospective analysis of 140 GC patients was performed. BMI was measured at both the initial surgical visit and then again at the time of hospitalization for surgery. ΔBMI/day was determined. Associations with time to surgery, intraoperative blood loss, tumor stage, and survival were determined. ΔBMI/day was strongly associated with time to surgery (P = 0.001), magnitude of intraoperative blood loss, tumor stage, progression-free survival (PFS), and overall survival (OS) (all Ps
Fields of Study & Subjects
Bariatric Surgery and Outcomes
Cancer Risks and Factors
Gastric Cancer Management and Outcomes
Publication details
- Journal / source
- Nutrition and Cancer
- Publisher
- Informa UK Limited
- Volume
- 78
- Issue
- 8-9
- Pages
- 627–636
- Publication date
- 6 August 2026
- Language
- EN