Methodological considerations in evaluating the impact of adenotonsillectomy on asthma control in children
Abstract
This letter provides a constructive appraisal of the methodological aspects of Alenezi et al.’s systematic review and meta-analysis examining the impact of adenotonsillectomy on asthma control in children. The authors are commended for their adherence to PRISMA guidelines and for synthesizing data from a large cohort of over 74,000 participants. However, the reliance on observational studies limits causal inference, and the interpretation of heterogeneity could be strengthened through the inclusion of prediction intervals and subgroup analyses. Future research employing advanced statistical approaches and standardized outcome measures would further enhance the methodological rigor and clinical relevance of this valuable work.
Fields of Study & Subjects
Asthma and respiratory diseases
Delphi Technique in Research
Obstructive Sleep Apnea Research
Publication details
- Journal / source
- Journal of Asthma
- Volume
- 63
- Issue
- 5
- Pages
- 635–636
- Publication date
- 5 January 2026
- Language
- EN