Multi-target stool DNA test adherence among individuals screened for colorectal cancer through the US Defense Health Agency
Abstract
Objective Multi-target stool DNA (mt-sDNA) testing has demonstrated higher screening adherence compared with other colorectal cancer (CRC) screening modalities. Members of the US military tend to have higher CRC screening rates, but adherence to mt-sDNA testing among service members has not been adequately studied.Methods Mt-sDNA test adherence within one year and time to kit return was measured for individuals aged 45–64 years prescribed mt-sDNA tests through the Defense Health Agency (DHA) from April 26, 2022 to October 26, 2024. Logistic regression analysis was performed to determine demographic factors associated with adherence.Results A total of 62,209 patients were included. Overall, mt-sDNA test adherence was 80.6%. Logistic regression analysis demonstrated that patients with median household income >$125k (odds ratio [OR] 1.17, 95% CI 1.04–1.32, p = 0.007, ref:
Fields of Study & Subjects
Colorectal Cancer Screening and Detection
Genetic factors in colorectal cancer
Global Cancer Incidence and Screening
Publication details
- Journal / source
- Current Medical Research and Opinion
- Publisher
- Informa UK Limited
- Volume
- 42
- Issue
- 2
- Pages
- 195–203
- Publication date
- 1 February 2026
- Language
- EN