Investigating the pathogenicity of novel non-pathogenic Avibacterium paragallinarum isolates and their protective potential against infectious coryza

Avian Pathology 2026 Open access

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Authors: Mostafa M. S. Shelkamy, Callie Fay, Amro Hashish, Eman Gadu, Mariela Srednik, Onyekachukwu Osemeke, Maria Chaves, Caroline Comyn, Qijing Zhang, Yuko Sato, Mohamed M. El-Gazzar
DOI: 10.1080/03079457.2026.2649913
Cited by: 1
References: 36

Abstract

< 0.05). Four weeks later (Phase II), G1-G7, as well as the original positive control group, were re-challenged with the same C1 isolate to assess protection. G1-G7 developed clinical signs, infraorbital sinus gross and histopathological lesions comparable to the new positive control. In conclusion, the study results match field observations and confirm the novel npAP isolates are non-pathogenic to chickens. Additionally, npAP isolates do not confer protection against circulating Midwestern pAP serovar C1. Given their prevalence in NHL flocks in the US, npAP should be ruled out before confirming IC diagnosis in flocks without clinical signs.

Fields of Study & Subjects

Microbial infections and disease research Aquaculture disease management and microbiota Streptococcal Infections and Treatments

Publication details

Journal / source
Avian Pathology
Publisher
Informa UK Limited
Volume
55
Issue
3
Pages
343–360
Publication date
4 May 2026
Language
EN