Innovative applications and future prospects of Raman spectroscopy in precision management of cancer radiotherapy and chemotherapy
Abstract
In the era of precision medicine, radiotherapy and chemotherapy continue to serve as cornerstone modalities for cancer treatment. However, their management is fraught with challenges. Significant interindividual variability in therapeutic efficacy and adverse effects is observed, attributable to inherent differences among patients. Moreover, conventional tumor monitoring techniques are limited in their capacity to track real - time tumor metabolic dynamics and microenvironmental alterations. Raman spectroscopy, an emerging nondestructive technology, offers a novel approach to the precise management of these therapies by enabling real-time, noninvasive monitoring of tumor biological characteristics and treatment responses, leveraging its high sensitivity (detection limit of surface-enhanced Raman spectroscopy: 10−9M), subcellular spatial resolution (
Fields of Study & Subjects
Spectroscopy Techniques in Biomedical and Chemical Research
Advanced Radiotherapy Techniques
Optical Imaging and Spectroscopy Techniques
Publication details
- Journal / source
- Applied Spectroscopy Reviews
- Publisher
- Informa UK Limited
- Volume
- 61
- Issue
- 8
- Pages
- 895–937
- Publication date
- 12 January 2026
- Language
- EN