Integrative multi-omics Mendelian randomization reveals key lipid metabolism genes as therapeutic targets for diabetic nephropathy pathogenesis

Renal Failure 2026 Open access

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Authors: Shan Liu, Yan Xia, Lin Ding, Mingxia Zhang, 王网珍, Junying Zhou, L J Liu
DOI: 10.1080/0886022x.2026.2671460
Cited by: 1
References: 40

Abstract

expression was sparse, with no evident disease-associated shifts. These findings indicate discordance between genetically inferred risk effects and observed expression patterns, suggesting complex regulatory mechanisms.

Fields of Study & Subjects

Chronic Kidney Disease and Diabetes Genetic Associations and Epidemiology Renal Diseases and Glomerulopathies

Publication details

Journal / source
Renal Failure
Publisher
Informa UK Limited
Volume
48
Issue
1
Pages
2671460–2671460
Publication date
31 May 2026
Language
EN