Reno-protective mechanisms of curcumin in diabetic nephropathy
Abstract
Curcumin has a pivotal role in diabetic nephropathy (DN), intervening in its progression through molecular, pathological, and clinical levels. This review systematically summarizes how curcumin modulates multiple pathways, ameliorates pathological alterations, and improves the metabolic disorders in DN. However, its clinical efficacy is constrained by low bioavailability. Consequently, this work provides novel perspectives for the multidimensional intervention of DN and offers strategies for optimizing drug delivery systems.
Fields of Study & Subjects
Curcumin's Biomedical Applications
Chronic Kidney Disease and Diabetes
Natural Antidiabetic Agents Studies
Publication details
- Journal / source
- Journal of Asian Natural Products Research
- Pages
- 1–17
- Publication date
- 4 March 2026
- Language
- EN