Plant-derived extracellular vesicles: multifunctional nanocarriers bridging food bioactivity and therapeutics

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Authors: Zeqian Yang, Shuyuan Shi, Boqing Yao, Zixin Han, R Y Wu, Pinglan Li, Nan Shang
Cited by: 1
References: 114

Abstract

Plant-derived extracellular vesicles (PDEVs) are nanoscale lipid bilayer particles secreted by plant cells, carrying various bioactive molecules and exhibiting good biocompatibility and safety. They have emerged as promising candidates for functional food compounds and active delivery carriers. This review summarizes recent advances in the extraction, purification, characterization, and engineering of PDEVs, highlighting their multiple application potentials in the food field, especially in functional enhancement, bioactive delivery, and high-value utilization of agricultural by-products. Despite their advantages, large-scale application remains limited by technical challenges, necessitating further systematic research.

Fields of Study & Subjects

Extracellular vesicles in disease Nanoplatforms for cancer theranostics Advanced Drug Delivery Systems

Publication details

Journal / source
Critical Reviews in Food Science and Nutrition
Publisher
Informa UK Limited
Volume
66
Issue
30
Pages
1–17
Publication date
27 June 2026
Language
EN