Exploring the anticancer potential of thienoquinoline derivatives: a comprehensive review
Abstract
Heterocyclic scaffolds represent crucial frameworks in modern drug development owing to their wide range of biological effects. Among these, quinoline derivatives exhibit notable antibacterial, anti-inflammatory, antimalarial, and anticancer activities. Thienoquinoline, a fused analogue of quinoline, has recently emerged as a promising structure with significant antiproliferative potential. Research findings suggest that these compounds can modulate vital molecular pathways responsible for cancer progression and cell survival. This review highlights current insights into the biological evaluation and significance of thienoquinoline derivatives, emphasizing their prospective utility as antiproliferative agents.
Fields of Study & Subjects
Synthesis and biological activity
Synthesis and Characterization of Heterocyclic Compounds
Synthesis and bioactivity of alkaloids
Publication details
- Journal / source
- Phosphorus, sulfur, and silicon and the related elements
- Publisher
- Informa UK Limited
- Volume
- 201
- Issue
- 4
- Pages
- 349–360
- Publication date
- 2 January 2026
- Language
- EN