A simplified method for 2-( N -aryol)benzimidazole synthesis

Phosphorus, sulfur, and silicon and the related elements 2026

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Authors: Ratna Babu Gunturu, Prasanna Babu Racheeti, Ramana Tamminana, Rameshraju Rudraraju
DOI: 10.1080/10426507.2026.2627268
Cited by: 0
References: 50

Abstract

We have developed an alternative synthetic route for the manufacturing of 2-(N-benzamido)benzimidazoles using a cross-coupling strategy. It is evident from the experimental results and feasible mechanism that the current method involves intra-molecular C–N cyclization. This method works very well with cheap, air-stable, and readily available iron sources as a catalyst. Furthermore, this method makes it possible to easily create a library of 2-(N-benzamido) benzimidazoles in moderate to high yields.

Fields of Study & Subjects

Catalytic Cross-Coupling Reactions Catalytic C–H Functionalization Methods Synthesis and biological activity

Publication details

Journal / source
Phosphorus, sulfur, and silicon and the related elements
Volume
201
Issue
5
Pages
737–742
Publication date
8 February 2026
Language
EN