KRAS internal tandem duplications and alternative driver variants in BRAF Val600Glu negative hairy cell leukemia

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Authors: P. Blombery, Sean McKeague, Benjamin Hartog, T. Nguyen, E. R. Thompson, Peter Presgrave, F. Roncolato, J. F. Seymour, David Ritchie, Sean Michael Grimmond, M. Wolf, D. Westerman
Cited by: 1
References: 7

Abstract

The BRAF Val600Glu activating mutation is present in the vast majority of patients with hairy cell leukemia (HCL) [1]. The activation of the MAPK pathway driven by this mutation is central to the p...

Fields of Study & Subjects

Chronic Lymphocytic Leukemia Research Cutaneous lymphoproliferative disorders research Lymphoma Diagnosis and Treatment

Publication details

Journal / source
Leukemia & lymphoma/Leukemia and lymphoma
Publisher
Informa UK Limited
Volume
67
Issue
5
Pages
1202–1204
Publication date
13 January 2026
Language
EN