Clinicopathological features and management of IgM multiple myeloma and Waldenstrom macroglobulinemia
Abstract
Waldenström macroglobulinemia (WM) is the most common malignancy associated with an IgM paraprotein, but in rare cases, a clonal IgM may be the result of IgM multiple myeloma (IgM-MM). Although there are some overlapping features associated with these two entities, there are specific characteristics that can help differentiate IgM-MM from WM. In each patient a thorough clinical, pathologic, and genomic evaluation is required to distinguish these conditions and allow for accurate diagnosis and appropriate treatment.
Fields of Study & Subjects
Chronic Lymphocytic Leukemia Research
Multiple Myeloma Research and Treatments
Celiac Disease Research and Management
Publication details
- Journal / source
- Leukemia & lymphoma/Leukemia and lymphoma
- Publisher
- Informa UK Limited
- Volume
- 67
- Issue
- 5
- Pages
- 989–996
- Publication date
- 21 January 2026
- Language
- EN