Chimeric antigen receptor T-cell therapy induces complete remission in a patient with concurrent CLL with CNS involvement and multiple sclerosis

Leukemia & lymphoma/Leukemia and lymphoma 2026

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Authors: Dermot J. Murphy, Siba El Hussein, Angela Applebee, Alissa Thomas, James N. Gerson
DOI: 10.1080/10428194.2026.2682293
Cited by: 1
References: 28

Abstract

In a patient with chronic lymphocytic leukemia (CLL) involving the central nervous system, and concurrent multiple sclerosis (MS), CD19-directed CAR T-cell therapy led to complete remission of CLL and marked improvement in MS disease burden.

Fields of Study & Subjects

Chronic Lymphocytic Leukemia Research CAR-T cell therapy research Multiple Sclerosis Research Studies

Publication details

Journal / source
Leukemia & lymphoma/Leukemia and lymphoma
Publisher
Informa UK Limited
Volume
67
Issue
10
Pages
2057–2063
Publication date
7 June 2026
Language
EN