Experimental validation of anti-bacterial property of Tragia involucrata plant extracts and its fractions

Journal of Herbs Spices & Medicinal Plants 2026

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Authors: Amulraj Panneerselvam, Srikanth Pichai Pillai, Sivasakthi Paramasivam, Senthamil Selvan P, Sundara Dhakshinamurthy Saraswathy, Sanmuga Priya Ekambaram
DOI: 10.1080/10496475.2026.2613974
Cited by: 0
References: 36

Abstract

The present study was carried out to perform anti-bacterial screening of extracts and fractions of T. involucrata and to evaluate its mechanism of action. The methanolic leaf extract (MLE) exhibited a more potent anti-microbial effect than the methanolic root extract (MRE) against E. coli, B. subtilis, S. typhimurium, K. pneumoniae, and S. faecalis. Among the fractions of MLE, the methanolic fraction (MF), and the ethyl acetate fraction (EF) showed potent anti-bacterial action against the pathogens. Both MLE and MF showed maximal inhibition against biofilm formation and increased the uptake of crystal violet against E. coli and K. pneumoniae.

Fields of Study & Subjects

Essential Oils and Antimicrobial Activity Medicinal Plant Research Bacterial biofilms and quorum sensing

Publication details

Journal / source
Journal of Herbs Spices & Medicinal Plants
Volume
32
Issue
2
Pages
255–277
Publication date
13 January 2026
Language
EN