Targeting PICK1 in drug discovery: from PDZ inhibition to next-generation BAR and bivalent modalities
Abstract
1. Protein Interacting with C-Kinase 1 (PICK1) is a membrane scaffolding protein recognized for its binding to protein kinase C α (PKCα) and its essential role in synaptic plasticity [1–4]. PICK1 i...
Fields of Study & Subjects
Neuroscience and Neuropharmacology Research
Protein Kinase Regulation and GTPase Signaling
Chemical Synthesis and Analysis
Publication details
- Journal / source
- Expert Opinion on Therapeutic Targets
- Volume
- 30
- Issue
- 2
- Pages
- 97–101
- Publication date
- 29 January 2026
- Language
- EN