Diketopiperazines from marine-derived Exserohilum sp. M1-6

Natural Product Research 2026

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Authors: Rui Xu, Jianjian Wang, Changyu Liu, Xuefang Yang, Minjun Chen, Zihan Jin, Shengyan Zheng, P. Li, Cong Wang, Shugeng Cao
DOI: 10.1080/14786419.2025.2610766
Cited by: 0
References: 24

Abstract

A new diketopiperazine (1) and 11 known compounds (2–12) were isolated from marine-derived Exserohilum sp. M1-6. The structure and the absolute configuration of compound 1 were determined by NMR, HRESIMS and electronic circular dichroism (ECD) data. The pro-angiogenic activity of compounds 2–12 were evaluated on the basis of a zebrafish model. The results showed that compounds 3, 11 and 12 had pro-angiogenic activity at a concentration of 40 μM.

Fields of Study & Subjects

Marine Sponges and Natural Products Microbial Natural Products and Biosynthesis Seaweed-derived Bioactive Compounds

Publication details

Journal / source
Natural Product Research
Pages
1–7
Publication date
4 January 2026
Language
EN