Imazalil at high plasma concentrations: implications for neutrophil immunophenotype

Journal of Immunotoxicology 2026 Open access

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Authors: Wioletta Ratajczak–Wrona, Małgorzata Rusak, Olga Diana Drezek, Joanna Chociej-Stypułkowska, Agnieszka Iwaniuk, Katarzyna Bielawska, Jolanta Wrobel, Agnieszka Żebrowska, Marzena Garley, Luiza Czaczkowska, Milena Dabrowska, Wojciech Miltyk
+5 more Piotr Radziwon, Sławomir Wołczyński, Dariusz Skarżyński, Barbara Pucelik, Ewa Jablonska
DOI: 10.1080/1547691x.2026.2672428
Cited by: 1
References: 34

Abstract

neutrophils. No changes in the percentage of neutrophils expressing the analyzed molecules were observed in the presence of testosterone. In conclusion, imazalil modulates the neutrophil immunophenotype, which may inhibit functions such as adhesion, migration, chemotaxis, and phagocytosis. Consequently, this may predispose individuals exposed to this compound to innate immunity disorders.

Fields of Study & Subjects

Neutrophil Myeloperoxidase and Oxidative Mechanisms Blood disorders and treatments Platelet Disorders and Treatments

Publication details

Journal / source
Journal of Immunotoxicology
Publisher
Informa UK Limited
Volume
23
Issue
1
Pages
2672428–2672428
Publication date
21 May 2026
Language
EN