Optineurin, an autophagy adaptor, stabilizes Rictor to maintain Akt/mTOR signaling and antigen presentation
Abstract
: OPTN: Optineurin; mTORC1: mammalian target of rapamycin complex 1; mTORC2: mammalian target of rapamycin complex 1; Rictor: Rapamycin-Insensitive Companion of mTOR.
Fields of Study & Subjects
Autophagy in Disease and Therapy
Endoplasmic Reticulum Stress and Disease
PI3K/AKT/mTOR signaling in cancer
Publication details
- Journal / source
- Autophagy
- Publisher
- Informa UK Limited
- Pages
- 1–3
- Publication date
- 18 June 2026
- Language
- EN