Alcohol metabolism and psychomotor function after consuming different alcoholic beverages: baijiu, beer and wine

Objective This study aimed to characterize the pharmacokinetics of blood alcohol and acetaldehyde, quantify acute psychomotor impairment, and evaluate the influence of beverage type under standardized alcohol dosing in healthy Han Chinese adults.Methods Eleven participants with the ALDH2*1/*1 genotype consumed baijiu, beer, and red wine on separate occasions at a standardized alcohol dose of 0.8 g/kg. Blood alcohol concentrations and blood acetaldehyde concentrations were measured for 8 h. Psychomotor function was evaluated with four validated tasks, and mood states were assessed with the Profile of Mood States and the Biphasic Alcohol Effects Scale.Results The earliest blood alcohol concentration peak was observed in six participants after baijiu, four after red wine, and one after beer; similarly, the earliest blood acetaldehyde concentration peak occurred in six participants after baijiu, two after red wine, and three after beer. All beverages induced time-dependent psychomotor impairments (P 0.05). Mood state assessments also revealed significant time effects (P