The impact of a multidisciplinary team evaluation on the diagnosis and management of acute and chronic pancreatitis in a tertiary referral center

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Authors: Gaetano Lauri, Matteo Tacelli, Gabriele Capurso, the San Raffaele Pancreas Center Pancreatitis Multidisciplinary Team, Giulio Belfiori, Diego Palumbo, Francesca Aleotti, M. Lanzillotta, R Ponz de Leon Pisani, Paolo Biamonte, Francesco Frigo, Rubino Nunziata
+18 more Niccolò Bina, Ilaria Marengon, Piera Zaccari, Giuseppe Vanella, Livia Archibugi, Maria Chiara Petrone, Gemma Rossi, Claudio Doglioni, Domenico Tamburrino, Alberto Mariani, Alberto Malesci, Silvio Danese, Paoletta Preatoni, Emanuel Della‐Torre, Stefano Crippa, F. De Cobelli, Falconi Massimo, Paolo Giorgio Arcidiacono
Cited by: 0
References: 37

Abstract

BACKGROUND: Multidisciplinary team meetings (MTM) are crucial in benign conditions such as acute pancreatitis (AP) and chronic pancreatitis (CP). Our aim was to evaluate the impact of MTM on the diagnosis and management of AP and CP in a tertiary referral center. RESEARCH DESIGN AND METHODS: This retrospective study analyzed 232 patients with AP/CP discussed with biweekly MTM (10/2020-06/2024). The patients were classified according to etiology or complication management, recording diagnostic and therapeutic outcomes over six months. RESULTS: Of 536 referred patients, 232 were analyzed (142 AP, 90 CP). In AP subgroup, MTM revised etiology in 34.4% of cases and identified a cause in 45.5% of idiopathic AP. MTM also ensured successful management of AP complications in 100% of cases, including endoscopic or surgical interventions for pseudocysts and walled-off necrosis. In CP, the diagnosis was revised in 38.9%, with a cause identified in 45.5% of idiopathic cases. MTM effectively guided CP complication management, with 55% of cases managed surgically and 10% endoscopically. MTM identified 6 cases of low-grade pancreatic intraepithelial neoplasia and 9 previously undiagnosed pancreatic ductal adenocarcinomas (PDAC) across both cohorts. CONCLUSIONS: In high-volume centers, MTM enhance diagnostic accuracy and optimize the tailored management of benign pancreatic diseases.

Fields of Study & Subjects

Pancreatitis Pathology and Treatment Gallbladder and Bile Duct Disorders Pancreatic and Hepatic Oncology Research

Publication details

Journal / source
Expert Review of Gastroenterology & Hepatology
Volume
20
Issue
2
Pages
191–199
Publication date
1 February 2026
Language
EN