Is exercise a medicine provided by digital therapeutics for people with NCDs? A scoping review protocol

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Authors: Davide Grillo, Mattia Cecconi, Gianluca Ossola, Alessia Stefanello, Silvia Ciceri, Veronica Romano, Mirko Zitti, Giacomo Basso, R. Pavan, Michele Perrucchini, Giuseppe Dallapellegrina, Gabriele Carbonetti
+12 more Federica Pagani, Claudio Colombo, Camilla Vignozzi, Nicolò Tassan Viol, Ahmed Lahmar, Ignazio Geraci, Silvia Bargeri, Eugenio Santoro, Błażej Cieślik, Silvia Zangarini, Stefano Bargellesi, Paweł Kiper
Cited by: 0
References: 59

Abstract

INTRODUCTION: Physical activity is widely recognised as effective in preventing and managing non-communicable diseases (NCDs). Digital health innovations can facilitate the delivery of physical exercise programs for this population. Digital therapeutics (DTx) could transform healthcare delivery, including how digital exercise therapy is provided. We aim to perform a scoping review to systematically explore whether and how exercise is provided by DTx for preventing and managing NCDs. METHODS: This protocol follows the Joanna Briggs Institute (JBI) methodology for scoping reviews and is reported according to JBI best practice guidance. A comprehensive search strategy will be performed in MEDLINE, CINAHL, Cochrane, PEDro and Google to identify existing DTx for preventing and treating NCDs, and which of those provide exercise therapy as intervention. Key data of the included studies will be charted descriptively and supplemented by summary tables. ETHICS AND DISSEMINATION: This scoping review does not require ethics review and approval. Our target audience for this review will be DTx manufacturers, health policy makers, clinicians, researchers, patients and other relevant stakeholders, in order to highlight gaps and potential of physical exercise provided by DTx. Results will be disseminated through peer-reviewed publications, online platforms and conference presentations. PROTOCOL REGISTRATION NUMBER: https://osf.io/fyqt8.

Fields of Study & Subjects

Mobile Health and mHealth Applications Cardiovascular and exercise physiology Cardiovascular Effects of Exercise

Publication details

Journal / source
Disability and Rehabilitation Assistive Technology
Volume
21
Issue
4
Pages
1578–1592
Publication date
10 January 2026
Language
EN