Analysis of chronic pain patients at a multidisciplinary spine center

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Authors: Lisa R. Witkin, Jessica Kim, Jacky Choi, Silis Y. Jiang, Jonathan N. Tobin
Cited by: 0
References: 21

Abstract

Objective The primary objective is to characterize patients presenting to a multidisciplinary spine center to understand sociodemographic features, pain characteristics, and functional status across diagnoses. The secondary objective is to identify factors associated with worse outcomes in radiculopathy patients.Methods In this retrospective, registry-based cohort study, we extracted questionnaire and EHR data for 10,069 patients. Baseline sociodemographic, clinical, and pain-related were examined across the top 10 diagnostic categories. Thereafter, we performed an analysis of radiculopathy patients (n = 653) using GLMM with random intercepts to identify baseline factors associated with changes in NRS and PROMIS-PI.Results At presentation, patients had moderate pain intensity (mean NRS:5.1, SD:2.1), significant impairment in PROMIS-PI (mean:64.6, SD:7.9), and PROMIS-PF (mean:37.7, SD:8.9), regardless of the diagnosis. Longitudinal analysis of radiculopathy patients identified multiple statistically significant factors (p < 0.05) associated with worse outcomes, including sleep interference, depression/anxiety, smoking, BMI, and being female, Black/African American, or Asian race.Conclusions This study explores predictors of poor outcomes that may identify opportunities for interventions targeting modifiable risk factors and highlights the need for further research into how health disparities influence treatment outcomes. Identifying non-responders could improve selecting effective treatments through precision care, ultimately reducing costs and disability associated with chronic pain.

Fields of Study & Subjects

Musculoskeletal pain and rehabilitation Spine and Intervertebral Disc Pathology Pain Management and Treatment

Publication details

Journal / source
Pain Management
Volume
16
Issue
5
Pages
405–418
Publication date
10 February 2026
Language
EN