Medial femoral condyle free flap for reconstructions of medication related osteonecrosis of the jaw

Case Reports in Plastic Surgery and Hand Surgery 2026 Open access

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Authors: Derek C. Wenger, Caleb W. Brown, Phillip L. Nichols, Hannah Tan, Jeremy M. Powers
DOI: 10.1080/23320885.2026.2619311
Cited by: 1
References: 32

Abstract

Medication-related osteonecrosis of the jaw (MRONJ) is a rare complication of antiresorptive therapy that may require free tissue reconstruction. A 57-year-old woman with metastatic breast cancer developed refractory mandibular MRONJ after intravenous zoledronic acid and underwent reconstruction with a medial femoral condylar (MFC) free flap. She recovered without complications and maintained normal function at two-year follow-up. This case supports the MFC free flap as a viable option for small, partial-thickness mandibular defects in selected patients with MRONJ.

Fields of Study & Subjects

Bone health and treatments Oral health in cancer treatment Bone and Joint Diseases

Publication details

Journal / source
Case Reports in Plastic Surgery and Hand Surgery
Publisher
Informa UK Limited
Volume
13
Issue
1
Pages
2619311–2619311
Publication date
27 January 2026
Language
EN