Continuous positive airway pressure efficacy in sleep apnea syndrome coexisting with empty nose syndrome: A case report

Empty nose syndrome (ENS) is an iatrogenic condition characterized by paradoxical nasal obstruction and dyspnea, despite a patent nasal cavity. Although a high co-occurrence of ENS and sleep apnea syndrome (SAS) has been documented, reports evaluating therapeutic efficacy are few. In this case report, we described a 51-year-old man who developed nasal obstruction, globus, and insomnia after posterior nasal neurectomy, endoscopic submucosal turbinectomy, and endoscopic septoplasty at another hospital. He presented with persistent symptoms consistent with ENS. Full-night polysomnography (PSG) revealed an apnea–hypopnea index (AHI) of 27 events/h, indicating moderate SAS. Continuous positive airway pressure (CPAP) therapy was initiated and found to be effective. CPAP therapy may be beneficial when SAS complicates ENS, even with a capacious nasal airway.