Modeling the effect of alcohol consumption on the progression dynamics of Hepatitis C infection with treatment

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Authors: Agnes Mbeine Asiimwe, Michael Byamukama, Martin Karuhanga
Cited by: 1
References: 23

Abstract

This research introduces a model that integrates a logistic approach to alcohol consumption to delve into the effect of alcohol consumption on the advancement of hepatitis C infection, evaluates the effects of addressing hepatitis C treatment and reducing alcohol consumption to minimal levels in the control of hepatitis C infection. The hepatitis C model was well established and biologically reasonable, indicating that all model solutions were non-negative and associated with non-negative initial conditions. Stability analysis revealed that the disease-free and endemic equilibrium points were locally and globally asymptotically stable whenever the basic reproduction number, [Formula: see text] and [Formula: see text] respectively. Sensitivity and numerical analysis of the model showed that improving treatment for individuals with chronic infection, along with reducing alcohol consumption, led to a notable decrease in the number of people affected by chronic infection.

Fields of Study & Subjects

Hepatitis C virus research Alcohol Consumption and Health Effects Mathematical and Theoretical Epidemiology and Ecology Models

Publication details

Journal / source
Mathematics in Medical and Life Sciences
Publisher
Informa UK Limited
Volume
3
Issue
1
Publication date
9 February 2026
Language
EN