A34-05 Blood Eosinophil Dynamics in COPD: Impact of Exacerbations and Corticosteroid Use in a Nationwide Study
Abstract
Abstract Background Blood eosinophil counts are pivotal for guiding advanced therapies in Chronic Obstructive Pulmonary Disease (COPD), yet their long-term consistency is poorly understood. This study aimed to characterize the longitudinal variability of blood eosinophils and identify factors associated with their instability within a large, real-world COPD population. Methods We conducted a nationwide, register-based cohort study of 63,517 Danish patients with COPD, each with at least four eosinophil measurements over a median follow-up of 3.4 years. Eosinophil levels were categorized into three groups:
Fields of Study & Subjects
Chronic Obstructive Pulmonary Disease (COPD) Research
Respiratory and Cough-Related Research
Asthma and respiratory diseases
Publication details
- Journal / source
- American Journal of Respiratory and Critical Care Medicine
- Publisher
- Oxford University Press (OUP)
- Volume
- 212
- Issue
- Supplement_1
- Publication date
- 1 May 2026
- Language
- EN