DNAvi: integration, statistics, and visualization of cell-free DNA fragment traces
Abstract
SUMMARY: DNAvi is a Python-based tool for rapid grouped analysis and visualization of cell-free DNA fragment size profiles directly from electrophoresis data, overcoming the need for sequencing in basic fragmentomic screenings. It enables normalization, statistical comparison, and publication-ready plotting of multiple samples, supporting quality control and exploratory fragmentomics in clinical and research workflows. AVAILABILITY AND IMPLEMENTATION: DNAvi is implemented in Python and freely available on GitHub at https://github.com/anjahess/DNAvi under a GNU General Public License v3.0, along with source code, documentation, and examples. An archived version is available under https://doi.org/10.5281/zenodo.18401705.
Fields of Study & Subjects
Molecular Biology Techniques and Applications
Cancer Genomics and Diagnostics
Genetic factors in colorectal cancer
Publication details
- Journal / source
- Bioinformatics
- Publisher
- Oxford University Press (OUP)
- Volume
- 42
- Issue
- 2
- Publication date
- 28 January 2026
- Language
- EN