A tale of two KRAS variants

British Journal of Dermatology 2026

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Authors: Will Swansson, Jessica McClatchy, Ingrid Winship, Laura Scardamaglia
DOI: 10.1093/bjd/ljag004
Cited by: 0
References: 8

Abstract

We report two patients with identical KRAS p.G12D variants but strikingly different vascular phenotypes: a high-flow arteriovenous malformation and an isolated capillary-predominant lesion. These cases expand the phenotypic spectrum of KRAS-associated vascular malformations and highlight the value in genetic testing, particularly in atypical presentations.

Fields of Study & Subjects

Vascular Malformations and Hemangiomas Vascular Malformations Diagnosis and Treatment Vascular Anomalies and Treatments

Publication details

Journal / source
British Journal of Dermatology
Volume
194
Issue
4
Pages
810–811
Publication date
7 January 2026
Language
EN