Topical probiotics in soybean concentrate for diabetic foot ulcers: a randomized controlled trial
Abstract
In this double-blind randomized controlled trial of 58 patients with 58 diabetic foot ulcers, a topical probiotic formulation in soybean concentrate significantly accelerated wound healing compared with placebo. The mean days to complete healing was 89.6 vs. 165.9 (P = 0.012), with higher healing rates from week 20 onwards. The treatment was safe and well tolerated, supporting topical probiotics as a promising adjunctive therapy for chronic diabetic foot ulcers.
Fields of Study & Subjects
Wound Healing and Treatments
Diabetic Foot Ulcer Assessment and Management
Bee Products Chemical Analysis
Publication details
- Journal / source
- British Journal of Dermatology
- Publisher
- Oxford University Press (OUP)
- Volume
- 194
- Issue
- 6
- Pages
- 1192–1194
- Publication date
- 25 March 2026
- Language
- EN