Survival after breast-conserving surgery and radiotherapy versus mastectomy: propensity score analyses within a randomized anaesthesiology trial

British journal of surgery 2026 Open access

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Authors: Charlotta Wadsten, Anders Berglund, Emma Söderberg, Greger Nilsson, Leif Bergkvist, Mats Enlund, Fredrik Wärnberg
DOI: 10.1093/bjs/znag036
Cited by: 1
References: 29

Abstract

BACKGROUND: Large randomized studies show equivalent survival after breast-conserving surgery (BCS) + adjuvant radiotherapy (RT) and mastectomy. In contrast, more recent observational studies suggest BCS + RT to be superior, but it is questionable whether patients in these treatment arms are comparable. Here, overall survival (OS) and breast cancer-specific survival (BCSS) after BCS + RT and mastectomy are compared within a randomized trial comparing intravenous and inhalation anaesthesia during breast cancer surgery. METHODS: The patient cohort was recruited from the randomized CAN-study. Patients with tumours >30 mm, patients with tumours

Fields of Study & Subjects

Breast Cancer Treatment Studies Global Cancer Incidence and Screening Prostate Cancer Diagnosis and Treatment

Publication details

Journal / source
British journal of surgery
Publisher
Oxford University Press (OUP)
Volume
113
Issue
4
Publication date
27 March 2026
Language
EN