Brain age trajectories and cognition after stroke in two longitudinal cohorts

Brain Communications 2026 Open access

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Authors: Gisle Berg Helland, Håkon Ihle-Hansen, Anne Hege Aamodt, Esten Høyland Leonardsen, Kaufmann Tobias, Brian Anthony B. Enriquez, Mona K Beyer, S. Andersson, H. Stangeland, Hege Ihle-Hansen, HF Harbo, Einar August Høgestøl
+1 more Guri Hagberg
DOI: 10.1093/braincomms/fcaf509
Cited by: 1
References: 35

Abstract

Abstract Brain age is a promising neuroimaging biomarker, reflecting biological aging, but long-term trajectories and predictive value for cognitive outcomes post-stroke remains unclear. This study aimed to characterize brain aging trajectories over 8 years following a first-ever stroke and to evaluate the predictive value of brain age estimates for long-term cognitive outcomes. We analysed data from working-age (

Fields of Study & Subjects

Acute Ischemic Stroke Management Dementia and Cognitive Impairment Research Stroke Rehabilitation and Recovery

Publication details

Journal / source
Brain Communications
Publisher
Oxford University Press (OUP)
Volume
8
Issue
1
Pages
fcaf509–fcaf509
Publication date
1 January 2026
Language
EN