Comment on ‘Nail matrix melanoma in adolescents and young adults: a retrospective dermoscopic study’: shifting the diagnostic paradigm by replacing ‘adult age’ with ‘after puberty’ for earlier detection

Clinical and Experimental Dermatology 2026

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Authors: Junhua Qi, Gang Nie
DOI: 10.1093/ced/llag039
Cited by: 0
References: 4

Abstract

This comment argues for a critical update to the diagnostic criteria for nail matrix melanoma. Based on recent evidence of cases in younger patients, we propose replacing the ‘adult age’ criterion in the ABCD rule with ‘after puberty’ to facilitate earlier detection. The shift underscores the importance of dermoscopic vigilance and timely biopsy in adolescents and young adults with atypical longitudinal melanonychia.

Fields of Study & Subjects

Cutaneous Melanoma Detection and Management Nail Diseases and Treatments Cancer and Skin Lesions

Publication details

Journal / source
Clinical and Experimental Dermatology
Volume
51
Issue
6
Pages
1099–1099
Publication date
23 January 2026
Language
EN