Fatal Transfusion-transmitted Severe Dengue in an Immunocompromised Host: Case Report and Systematic Literature Review

Clinical Infectious Diseases 2026

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Authors: Alexandre Mestre Tejo, Amaro Nunes Duarte-Neto, Jacqueline Alves Rena, Wdson Luís Lima Kruschewsky, Camila Malta Romano, Caio Santos de Souza, Raquel Gomes Catozo, Mariene R. Amorim, Cinthya dos Santos Cirqueira, Hermes Ryoiti Higashino, Bruno Garcia Pires, Ester Cerdeira Sabino
+3 more Alfredo Mendrone, Vanderson Rocha, Sílvia Figueiredo Costa
DOI: 10.1093/cid/ciag292
Cited by: 1
References: 21

Abstract

Transfusion-transmitted dengue remains a relevant risk during outbreaks. We report a transfusion-transmitted severe dengue case in a stem cell transplant recipient during the 2024 epidemic in Brazil, supported by phylogenetic linkage, evolving to a fatal outcome. This sentinel case highlights the potential severity of transfusion-transmitted dengue, particularly in immunocompromised hosts.

Fields of Study & Subjects

Mosquito-borne diseases and control Zoonotic diseases and public health Parasites and Host Interactions

Publication details

Journal / source
Clinical Infectious Diseases
Publisher
Oxford University Press (OUP)
Volume
83
Issue
2
Pages
234–238
Publication date
2 May 2026
Language
EN