Landiolol for rate control in decompensated heart failure due to atrial fibrillation: the LARISA trial

European Heart Journal Acute Cardiovascular Care 2026 Open access

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Authors: Marek Šramko, Ales Benak, Jakub Toman, Martin Kleissner, Michal Pazdernik, Josef Kautzner
DOI: 10.1093/ehjacc/zuag027
Cited by: 2
References: 8

Abstract

AIMS: Rate control of atrial fibrillation (AF) in acute heart failure (AHF) with reduced left ventricular ejection fraction (LVEF) is challenging. We evaluated the safety and efficacy of intensive rate control (IRC) using landiolol with adjunctive digoxin. METHODS AND RESULTS: Forty patients with AHF due to AF [heart rate (HR) > 130/min, LVEF 20% or

Fields of Study & Subjects

Cardiac electrophysiology and arrhythmias Atrial Fibrillation Management and Outcomes Heart Failure Treatment and Management

Publication details

Journal / source
European Heart Journal Acute Cardiovascular Care
Publisher
Oxford University Press (OUP)
Volume
15
Issue
8
Pages
622–626
Publication date
26 February 2026
Language
EN