Left ventricular reservoir strain in heart failure with preserved ejection fraction on cardiovascular pharmacotherapy

Abstract Backgroung Left atrial(LA) reservoir strain(RS) is measured by 2D speckle tracking echocardiography(STE). There are a number of studies that have shown both diagnostic and prognostic role of LA RS in heart failure with preserved ejection fraction(HFpEF). Purpose The aim of our study was to identify whether LV RS plays an important role for management of patients with HFpEF on cardiovascular pharmacotherapy. Methods We examined 85 patients with HFpEF(44 males and 41 females, 62±5 years) with concomitant cardiovascular diseases(chronic coronary syndromes, arterial hypertension, atrial fibrillation, valvular heart disease) and symptoms of HF. All patients received guideline directed medical therapy. Normal LA RS values were considered≥20%, pathologic values40 mm(2.3%), LV wall motion abnormalities-18 patients(21%), all patients LVEF>50%. The results have shown that 70 out of 85 cases(88.2%) LA RS