Clinical and economic impact of FFR-CT-guided decision making in patients with moderate coronary disease

Abstract Introduction Fractional flow reserve-computed tomography (FFR-CT) is a new tool to improve diagnostic accuracy. However, its impact in Spain remains untested. Purpose This study evaluates the clinical and economic implications of incorporating FFR-CT into routine practice in Spain, versus standard approach, in patients with moderate coronary stenosis. Methods This is a retrospective, observational, single-center intervention simulation study conducted on patients with stable chest pain who underwent a coronary CT angiography (July 2021 -December 2022) in Spain. Patients were eligible if they had a CAD-RADS 2.0 grading system of 3 (50–69% stenosis), body mass index