Cardiovascular magnetic resonance-derived left atrial function and left ventricular remodelling after reperfused anterior ST-elevation myocardial infarction

Abstract Introduction Adverse left ventricular (LV) remodelling is associated with increased mortality and heart failure following reperfused ST-segment elevation myocardial infarction (STEMI). While both LV global longitudinal strain (GLS) and left atrial (LA) strain have independently demonstrated significant prognostic value for risk assessment in STEMI, the optimal atrial or ventricular functional parameter for risk assessment remains unclear. Purpose To investigate the prognostic significance of atrial and ventricular function indices, to predict early adverse LV remodelling in patients with anterior STEMI. Methods A post-hoc analysis of the European intracoronary cooling evaluation in ST-elevation myocardial infarction (EURO-ICE) trial was performed. In this study, patients with large anterior wall STEMI underwent cardiovascular magnetic resonance (CMR) at baseline (