Recurrence of peripartum cardiomyopathy in subsequent pregnancy stratified by left ventricular function: a systematic review and meta-analysis

European Journal of Heart Failure 2026 Open access

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Authors: Hawani Sasmaya Prameswari, Cindya Perthy Iswandi, Jordan Budiono, Melawati Hasan, Dian Yaniarti Hasanah, Triwedya Indra Dewi, Johann Bauersachs, Karen Sliwa, Peter van der Meer
DOI: 10.1093/ejhf/xuag063
Cited by: 2
References: 24

Abstract

AIMS: Subsequent pregnancy in women with prior peripartum cardiomyopathy (PPCM) carries a risk of relapse and adverse maternal outcomes. This meta-analysis aimed to determine the recurrence of PPCM relapse and associated maternal and foetal outcomes during subsequent pregnancy, stratified by baseline (pre-subsequent pregnancy) left ventricular ejection fraction (LVEF). METHODS: A systematic review and meta-analysis was conducted in accordance with PRISMA guidelines. Nine databases were searched through June 2025 for cohort studies reporting subsequent pregnancy outcomes in women with prior PPCM, stratified as recovered (LVEF ≥50%) or non-recovered (LVEF

Fields of Study & Subjects

Cardiovascular Issues in Pregnancy Cardiac Structural Anomalies and Repair Chemotherapy-induced cardiotoxicity and mitigation

Publication details

Journal / source
European Journal of Heart Failure
Publisher
Oxford University Press (OUP)
Volume
28
Issue
3
Pages
385–396
Publication date
1 March 2026
Language
EN