Urinary sodium to guide diuretic therapy in acute heart failure: results of a national survey

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Authors: M Cobo Marcos, Joan Carles Trullàs, José Pérez-Silvestre, Ò Miró, Borja Quiroga, Sònia Mirabet, G Romero-González
Cited by: 2
References: 15

Abstract

BACKGROUND AND AIMS: Urinary sodium (uNa+) is a promising tool to guide diuretic therapy in acute heart failure (AHF), yet its real-world adoption is uncertain. We aimed to evaluate current practices, perceived utility, and barriers to uNa⁺-guided management among physicians managing AHF in Spain. METHODS: We conducted a nationwide cross-sectional electronic survey in June 2025 of clinicians from cardiology, internal medicine, emergency medicine, and nephrology. The questionnaire assessed the frequency and timing of uNa+ monitoring in inpatient and outpatient settings, thresholds for poor response, therapeutic adjustments, and perceived benefits and barriers. RESULTS: A total of 413 physicians responded: 138 (33%) from cardiology, 159 (39%) from internal medicine, 78 (19%) from emergency medicine, and 38 (9%) from nephrology. Overall, 70% reported measuring uNa+ during AHF hospitalization, but only 18% did so routinely. Outpatient application remained infrequent (32%). Nephrologists showed the highest usage in both inpatient (90%) and outpatient (61%) settings. The most frequent cut-off to define diuretic resistance was

Fields of Study & Subjects

Sodium Intake and Health Electrolyte and hormonal disorders Heart Failure Treatment and Management

Publication details

Journal / source
ESC Heart Failure
Publisher
Oxford University Press (OUP)
Volume
13
Issue
1
Publication date
8 January 2026
Language
EN