‘Veni, Vidi, Vaccini’: consensus-based vaccination pathway implementation in a paediatric tertiary hospital in Tuscany, Italy

Fragile paediatric patients are at higher risk of vaccine-preventable diseases, yet coverage remains suboptimal. Hospitalisation offers an opportunity to review and update immunisation, but fragmented practices create inequities, with access depending more on hospital context than clinical need. This study aimed to design, implement, and evaluate an in-hospital vaccination pathway for these patients. A mixed-methods approach was undertaken at Meyer Children's Hospital IRCCS, Florence, Italy. Baseline assessment included nine focus groups and an online questionnaire with healthcare professionals from units managing fragile patients, exploring practices, barriers, and needs. Findings informed the co-design of a pathway integrating documentation review, catch-up planning, and in-hospital delivery coordinated by the Immunology Unit. Administrative data on non-SARS-CoV-2 vaccinations in fragile patients (2022-2025) were analysed. Most respondents supported hospital-based vaccination (94.2%) but reported gaps in registry access, spaces, and training. Only 67.6% collected vaccination history systematically, 14.4% always mentioned vaccination in discharge letters, and 15.9% always recommended family immunisation. Despite acknowledging low influenza coverage (60.9% declared coverage