Altered natural killer cell function in children with severe malaria

ImmunoHorizons 2026 Open access

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Authors: Grace Turyasingura, Kagan A. Mellencamp, Ruth Namazzi, Robert Opika Opoka, Chandy C. John, Geoffrey T. Hart
DOI: 10.1093/immhor/vlaf070
Cited by: 0
References: 67

Abstract

Memory-like natural killer (NK) cells with enhanced antibody-dependent cellular cytotoxicity (ADCC) have correlated with protection from uncomplicated malaria in prior studies. However, the role of NK cells in severe malaria (SM) has not been characterized. In Ugandan sites with moderate and low malaria transmission, we evaluated NK cell (CD56bright, CD56dim, CD56neg) phenotype and ADCC function by flow cytometry in children

Fields of Study & Subjects

Malaria Research and Control Immune Cell Function and Interaction Invertebrate Immune Response Mechanisms

Publication details

Journal / source
ImmunoHorizons
Volume
10
Issue
1
Publication date
1 January 2026
Language
EN