Modeling Predicts Direct-Acting Antiviral Therapy for 5-Weeks May Cure Recent or Chronic Hepatitis C Infection Among People With Undetectable Viral RNA by Day 7

The Journal of Infectious Diseases 2026 Open access

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Authors: Ashish Goyal, Scott J. Cotler, Gail V Matthews, Kimberly Page, Tatyana Kushner, Ohad Etzion, Marianne Martinello, Harel Dahari
DOI: 10.1093/infdis/jiag260
Cited by: 3
References: 41

Abstract

BACKGROUND: Identifying individuals with hepatitis C virus (HCV) infection who could be cured with a shorter duration of direct-acting antivirals (DAA) therapy would support the effort to reach HCV elimination goals. To date, clinical studies of short duration DAA therapy based on early (e.g., days 2 or 7) HCV RNA levels (e.g.,

Fields of Study & Subjects

Hepatitis C virus research RNA Interference and Gene Delivery Virus-based gene therapy research

Publication details

Journal / source
The Journal of Infectious Diseases
Publisher
Oxford University Press (OUP)
Publication date
7 May 2026
Language
EN