2026 Updated good practice recommendations for outpatient parenteral antimicrobial therapy (OPAT) in adults and children in the UK

JAC-Antimicrobial Resistance 2026 Open access

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Authors: Ann L. Noble, Sanjay Patel, Ellie Birnie, Eileen Dorgan, Oyewole Christopher Durojaiye, Caroline Emilie, Achyut Guleri, H Green, Sara Hedderwick, Lucy Hinds, Monica V. Mahoney, Katie McIntyre
+6 more Fekade B. Sime, Owen Seddon, Julie Statham, Marie Woodley, M J Gilchrist, R Andrew Seaton
DOI: 10.1093/jacamr/dlag044
Cited by: 3
References: 279

Abstract

Good practice recommendations (GPRs) for outpatient parenteral antimicrobial therapy (OPAT) in the UK were first published in 2012 and 2015 for adult and paediatric OPAT, respectively, and then updated in 2019 as a combined set of recommendations for OPAT in all age groups. Since then, there has been ongoing expansion in national and global experience of OPAT. Here, we provide updated 2026 GPRs developed through a further review of the literature, expert consensus, and extensive consultation. As previously, these updated GPRs for OPAT in adults and children will support delivery of safe and effective OPAT by providing a set of quality indicators for OPAT in the UK regardless of the setting or service model.

Fields of Study & Subjects

Antibiotics Pharmacokinetics and Efficacy Pharmaceutical studies and practices Neonatal and Maternal Infections

Publication details

Journal / source
JAC-Antimicrobial Resistance
Publisher
Oxford University Press (OUP)
Volume
8
Issue
2
Pages
dlag044–dlag044
Publication date
9 March 2026
Language
EN