Poster Session II - A267 SYSTEMATIC REVIEW OF APPENDICEAL CROHN’S DISEASE: DIAGNOSIS AND MANAGEMENT

Abstract Background Crohn’s Disease (CD) limited to the appendix is a rare entity that is often not well documented in the literature, and its initial presentation can be difficult to differentiate from acute appendicitis. Diagnosis is often made postoperatively through histopathology. Current knowledge is limited to case reports and small series, standardized guidelines regarding its management. Aims We aim to review the current literature surrounding appendiceal Crohn’s Disease, including its clinical presentation, diagnosis, management, and patient outcomes. Methods A systematic search of Medline, Embase, Scopus, and PubMed was conducted. Studies reporting primary data on patients whose initial presentation was Crohn’s Disease limited to the appendix were included. Two reviewers (IG, WJH) independently screened and extracted data on demographic characteristics, clinical presentation, initial management, and post-treatment course. Results 31 studies met inclusion criteria (n = 120 patients). All the studies included are either case reports or retrospective case series. The mean age of diagnosis was 26 years (range 6-68). The mean duration of symptoms prior to presentation was 33 days (range