Prevalence of Plasmodium falciparum histidine rich protein 2/3 gene deletions affecting rapid diagnostic test performance in travellers

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Authors: Olivia Detzlhofer, Felix Lötsch, Jessica Kirchner, Renate Schneider, Matthias Weiss-Tessbach, Stefan Winkler, Julia Walochnik, Lorenz Schubert
Cited by: 0
References: 8

Abstract

In this traveller cohort, pfhrp2/3 deletions occurred in 4 of 115 (3.5%) patients, with no double deletions observed. Notably, 51.3% of patients had visited countries anticipated to surpass the WHO 5% pfhrp2/3 threshold by 2028. Continued monitoring of pfhrp2/3 deletions in non-endemic settings is needed to guide testing strategies.

Fields of Study & Subjects

Malaria Research and Control Travel-related health issues Vector-borne infectious diseases

Publication details

Journal / source
Journal of Travel Medicine
Volume
33
Issue
3
Publication date
21 February 2026
Language
EN