Circulating renin–angiotensin–aldosterone system markers in cats with non-hypertensive chronic kidney disease or systemic arterial hypertension
Abstract
BACKGROUND: Information on the classical and alternative circulating renin-angiotensin-aldosterone systems (RAAS) in cats with non-hypertensive chronic kidney disease (NHT-CKD) or systemic arterial hypertension (SAH) is limited. Age and diet affect the RAAS. HYPOTHESIS/OBJECTIVES: To compare serum equilibrium concentrations of angiotensin peptides and aldosterone in healthy cats and cats with NHT-CKD or untreated SAH, and to evaluate changes in these concentrations in hypertensive cats administered amlodipine. ANIMALS: Client-owned cats with NHT-CKD (serum creatinine ≥ 1.6 mg/dL, systolic blood pressure [SBP] < 160 mmHg; n = 17), SAH (SBP ≥ 160 mmHg or ≥ 150 mmHg with hypertensive ocular lesions; n = 6), or normal SBP (
Fields of Study & Subjects
Veterinary Medicine and Surgery
Cardiovascular Conditions and Treatments
Renin-Angiotensin System Studies
Publication details
- Journal / source
- Journal of Veterinary Internal Medicine
- Publisher
- Oxford University Press (OUP)
- Volume
- 40
- Issue
- 3
- Publication date
- 1 May 2026
- Language
- EN