Drawing parallels between amyloid PET in Alzheimer’s disease and amino acid PET in primary and secondary brain tumors

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Authors: Nelleke Tolboom, Antoine Verger, Matthias Preusser, Marjolein Geurts, Philip Scheltens, Nathalie L. Albert
Cited by: 0
References: 17

Abstract

The evolution of amyloid PET in Alzheimer's disease illustrates the potential path of amino acid PET in neuro-oncology. Initially seen as of limited value, amyloid PET ultimately enhanced diagnostic accuracy, guided management, and became central once therapies demonstrated PET-measured efficacy. Amino acid PET for CNS tumors is at a similar turning point. It refines diagnosis, distinguishes progression from treatment effects, and supports treatment planning. As demand grows and tracer access improves, amino acid PET could follow amyloid PET's trajectory: emerging as a key tool in precision medicine and clinical management and as a surrogate endpoint in therapeutic trials.

Fields of Study & Subjects

Medical Imaging Techniques and Applications Glioma Diagnosis and Treatment Neuroendocrine Tumor Research Advances

Publication details

Journal / source
Neuro-Oncology Advances
Volume
8
Issue
1
Pages
vdag043–vdag043
Publication date
1 January 2026
Language
EN