P-1311. Community-associated carbapenem-resistant gram-negative bacilli infection in Japan

Abstract Background Carbapenem-resistant Gram-negative bacilli (CR-GNB) infections are associated with high mortality and increased healthcare costs. While certain resistant pathogens, such as extended-spectrum β-lactamase-producing organisms, are increasingly identified in the community, reports of community-associated CR-GNB infections remain limited, particularly in high-income countries like Japan.Table 1.Demographic characteristics of patients with community-associated, healthcare-associated, and hospital-onset CR-GNB infections.CR-GNB, carbapenem-resistant Gram-negative bacilli; CA, community-associated; HA, healthcare-associated; HO, hospital-onset; IQR, interquartile range; IV, intravenous. a P values for comparisons among the three groups (CA, HA, HO) were calculated using the Kruskal–Wallis test for continuous variables and the chi-squared test for categorical variables. b Pairwise comparisons were performed using the Mann–Whitney U test for continuous variables and Fisher’s exact test for categorical variables. For multiple comparisons, a Bonferroni-corrected threshold of P